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Product data sheet PD-11545ES
SRE Luciferase Reporter Plasmid(SRE-Luc荧光素酶报告基因质粒) SRE Luciferase Reporter Plasmid(SRE-Luc荧光素酶报告基因质粒)
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SRE Luciferase Reporter Plasmid(SRE-Luc荧光素酶报告基因质粒)

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药物研究基因过表达RNAi表型分析
Product no.11545ES Sizes1 options Documents1 files SourceYeasen · Official
Cat. No. 11545ES03 现货 $3,365.00
Qty 1
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Cat.No Spec Price Status
11545ES03 1 μg $3,365.00 现货 Enquire
Submit enquiry Price is on application; bulk sizes can be sampled on request.

Overview

Specifications

Brand翌圣生物 Yeasen
Cat.No11545ES
Specification1 μg
Origin翌圣生物科技(上海)股份有限公司
应用方法 药物研究用于药物筛选和药效评估 基因过表达用于基因过表达的表型分析 RNAi表型分析用于RNAi干扰的表型分析
适用物种种属 哺乳动物
检测方法 荧光素酶检测
生物特性参数 试剂类型报告基因质粒 应用药物研究、基因过表达和RNAi表型分析 质粒类型哺乳动物真核表达载体 转录因子TCR/Elk1/SRF
技术参数 储存条件-20°C保存,有效期1年
实验类型 报告基因分析检测SRE转录因子活性 信号通路检测检测MAPK/ERK信号通路活性

FAQ

Q:该质粒和SREBF1及SREBF2的区别是什么?

A:Elk1/SRF结合的DNA序列通常称为Serum Response Element (SRE)。它与Sterol Regulatory Element(胆固醇调节元件)不同。Serum Response Element (SRE)是SRF结合的DNA序列,通常位于某些基因的启动子区域,参与调控与细胞生长、分化和应激反应相关的基因。

Documents & Citations

Published citations

[1] Katsch K, et al. Actin-dependent activation of serum response factor in T cells by the viral oncoprotein tip.Cell Commun Signal. 2012 Mar 3;10(1):5.

[2] Gozé C, et al. Involvement of tryptophan W276 and of two surrounding amino acid residues in the high constitutive activity of the ghrelin receptor GHS-R1a. Eur J Pharmacol. 2010 Sep 25;643(2-3):153-61.

[3] Notcovich C, et al. Histamine acting on H1 receptor promotes inhibition of proliferation via PLC, RAC, and JNK-dependent pathways. Exp Cell Res. 2010 Feb 1;316(3):401-11.

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