Recombinant Human IL-1 beta GMP Protein GMP级重组人白细胞介素-1β

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细胞培养间充质干细胞分化巨核细胞生成Th17细胞分化

Product no.90269ES Sizes4 options Documents1 files SourceYeasen · Official

Cat. No. 90269ES10

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Cat.No Spec Price Status

90269ES10 10 μg $1,428.00促~~$1,585.00~~ 现货 Enquire

90269ES50 50 μg $3,568.00促~~$3,965.00~~ 现货 Enquire

90269ES60 100 μg $6,545.00 现货 Enquire

90269ES80 1 mg $35,995.00 现货 Enquire

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Overview

Specifications

Brand翌圣生物 Yeasen

Cat.No90269ES

Specification本品重组人白介素-1β由大肠杆菌表达，以液体形式提供，高活性、高纯度、低内毒素。

Origin翌圣生物科技(上海)股份有限公司

应用方法 细胞培养促进未成熟树突状细胞（iDC）成熟 间充质干细胞分化促进MSCs分化为成骨细胞 巨核细胞生成促进PSC来源的巨核细胞生成 Th17细胞分化与TGF-β和IL-6协同刺激Th17细胞分化

适用物种种属人

检测方法 SDS-PAGE SEC-HPLC 鲎试剂法（LAL） ELISA qPCR

生物特性参数 蛋白类型细胞因子 种属来源Human（人） 生物活性描述The ED50 as determined by a cell proliferation assay using D10.G4.1 is less than 20 pg/mL. The specific activity of Human IL-1beta GMP Protein is >5.0 x 10^7 IU/mg which is calibrated against Interleukin-1 beta WHO International Standard (NIBSC code: 86/680). 应用用于促进未成熟树突细胞（iDC）成熟；使间充质干细胞（MSCs）分化为成骨细胞；促进来源于多能干细胞（PSC）的巨核细胞生成；与TGF-β和IL-6等细胞因子协同刺激Th17细胞分化。 产品别称Interleukin-1 beta IL-1β IL-1 IL1B IL-1b IL1-BETA IL-1F2 IL1F2IL-1 beta interleukin-1 beta preinterleukin 1 beta pro-interleukin-1-beta. 序列同源性与恒河猴的氨基酸序列同源性为96%，与犬、小鼠和大鼠的IL-1β氨基酸序列同一性为67%-78% 生物学功能促炎作用、免疫调节、促凋亡、促增殖

技术参数纯度>95% as determined by SDS-PAGE and HPLC analyses. 内毒素水平<0.01 EU/μg protein as determined by LAL method. 分子量Approximately 17.3 kDa. 制剂形式Liquid from 0.22 μm filtered solution in PBS. 活性ED50 <20 pg/mL; Specific activity >5.0 x 10^7 IU/mg. 储存条件-85~-65℃保存，有效期2年。 监管等级GMP级 外观Liquid 表达系统E.coli 标签No Tag 表达序列Ala117-Ser269 宿主残留蛋白Less than 0.5 ng/μg when tested by ELISA. 宿主残留DNALess than 20 ng/mg when tested by qPCR. 支原体检测Negative 无菌检测Negative 外源病毒Negative Accession号P01584