Recombinant Cynomolgus IL-23 alpha&Mouse IL-12 beta Protein,His Tag

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抗体药物靶点研究免疫学研究

Product no.94518ES Sizes3 options SourceYeasen · Official

Cat. No. 94518ES60

现货 ¥6,675.00

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94518ES60 100 μg ¥6,675.00 现货 Enquire

94518ES76 500 μg ¥22,285.00 现货 Enquire

94518ES25 25 μg ¥1,825.00 现货 Enquire

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Overview

Specifications

Brand翌圣生物 Yeasen

Cat.No94518ES

Specification高纯度、高活性、低内毒素、高批间一致性

Origin翌圣生物科技(上海)股份有限公司

应用方法 抗体药物靶点研究用于IL-23相关药物筛选与研发 免疫学研究研究IL-23信号通路

适用物种种属 食蟹猴 小鼠

检测方法 鲎试剂法(LAL) SDS-聚丙烯酰胺凝胶电泳(SDS-PAGE) 高效液相色谱(HPLC) 表面等离子共振(SPR)

生物特性参数 蛋白类型重组蛋白/细胞因子 (IL-23 alpha & IL-12 beta) 种属来源Cynomolgus (食蟹猴) IL-23 alpha & Mouse (小鼠) IL-12 beta 生物活性SPR实验显示可与食蟹猴IL-23R结合，亲和常数3.90 nM 应用IL-23相关免疫疾病研究和抗体药物靶点筛选 产品别称IL23 alpha IL12 β IL23 alpha&IL12 beta

技术参数纯度> 95% as determined by SDS-PAGE and HPLC 内毒素水平< 1.0 EU per μg by the LAL method 分子量Predicted MW: 19.5 (Cynomolgus IL23 alpha) & 35.8 (Mouse IL12 beta) kDa; migrates to 22 & 40-50 kDa under Tris-Bis PAGE due to glycosylation 制剂形式Lyophilized from 0.22μm filtered solution in PBS (pH 7.4) with 8% trehalose as protectant 活性Affinity constant 3.90 nM as determined by SPR assay 储存条件-25 ~ -15℃保存，有效期1年；复溶后，-85 ~ -65℃无菌保存，3个月 表达序列Val22-Pro189 (Cynomolgus IL-23 alpha) & Met23-Ser335 (Mouse IL-12 beta) 表达系统HEK293 标签N-His 外观Lyophilized Powder Accession编号A0A2K5TLV4-1 (Cynomolgus IL-23 alpha) & P43432-1 (Mouse IL-12 beta) 复溶方法开盖之前，先离心。使用蒸馏水复溶冻干的蛋白质，复溶浓度超过100 μg/mL。建议首次使用时将蛋白分装为每次实验用量，避免反复冻融。