Recombinant Human TREM2 (His Tag)

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抗体药物靶点研究神经退行性疾病研究

Product no.93778ES Sizes4 options SourceYeasen · Official

Cat. No. 93778ES25

现货 ¥1,195.00

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Cat.No Spec Price Status

93778ES25 25 μg ¥1,195.00 现货 Enquire

93778ES60 100 μg ¥4,445.00 现货 Enquire

93778ES76 500 μg ¥14,855.00 现货 Enquire

93778ES80 1 mg ¥29,715.00 现货 Enquire

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Overview

Specifications

Brand翌圣生物 Yeasen

Cat.No93778ES

Specification高纯度、高活性、低内毒素、高批间一致性

Origin翌圣生物科技(上海)股份有限公司

应用方法 抗体药物靶点研究靶点蛋白 神经退行性疾病研究阿尔茨海默病、多发性硬化等疾病机制研究

适用物种种属人

检测方法 酶联免疫吸附试验（ELISA） 聚丙烯酰胺凝胶电泳（SDS-PAGE） 鲎试剂法（LAL）

生物特性参数 蛋白类型重组蛋白/靶点蛋白/抗体药物靶点蛋白 种属来源人 生物活性描述TREM-2促进破骨细胞分化和功能、脂肪细胞炎症因子产生、胰岛素抵抗和吞噬清除细菌；在CNS中介导凋亡神经元、淀粉样斑块和细胞碎片的清除；与Plexin A1相互作用调节信号；可溶性TREM-2在多发性硬化患者脑脊液中升高应用阿尔茨海默病、Nasu-Hakola病、多发性硬化等疾病研究；抗体药物靶点

技术参数纯度> 95% as determined by SDS-PAGE 内毒素水平< 1.0 EU per μg by the LAL method 分子量Approximately 18.5 kDa; migrates to 28-40 kDa on Tris-Bis PAGE due to glycosylation 制剂形式Lyophilized from 0.22μm filtered solution in PBS (pH 7.4) with 5% trehalose as protectant before lyophilization 活性EC50 of 28.6 ng/ml determined by ELISA for Anti-TREM-2 Antibody binding 储存条件-25 ~ -15℃保存，有效期1年；复溶后，无菌条件下-85 ~ -65℃保存，有效期3个月 表达序列His19-Ser174 表达系统HEK293 标签C-His Accession号Q9NZC2.1 外观Lyophilized Powder 复溶方法开盖前先离心，使用蒸馏水复溶至浓度超过100 μg/mL，建议分装避免反复冻融 产品别称PLOSL2 TREM2 TREM-2 Trem2a Trem2b Trem2c